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Article

Chemo-radiotherapy: radiosensitizing nucleoside analogues (review).

1 Sept 1999

Abstract excerpt

The available knowledge on potential radiosensitizing nucleoside analogues with special focus on fludarabine and gemcitabine is reviewed. These analogues are prodrugs whose active triphosphate forms inhibit various enzymes involved in DNA synthesis and repair. Several properties of these analogues support their use as radiosensitizers. As repair inhibitors, they have the potential to increase the amount of...

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Identifiers

PMID: 10425285
DOI: 10.3892/or.6.5.949

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