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Article

Association of the IL-10 receptor A536G (S138G) loss-of-function variant with recurrent miscarriage.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jul 2014

Magdoud Kalthoum, Hellal Radhia, Zemni Ramzi, Touraine Renaud, Mahjoub Touhami, Almawi Wassim Y

Abstract excerpt

PROBLEM: We investigated the association of interleukin-10 receptor (IL10R1) loss-of-function variant A536G/S138G with recurrent pregnancy loss (RPL). METHOD OF STUDY: Study subjects comprised 300 women with ≥3 miscarriages, and 350 control women. RESULTS: Significantly higher 536G-allele frequency was seen in RPL cases, thus assigning pathogenic role for this allele. Significant difference in A536G/S138G...

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PMID: 24689510
DOI: 10.1111/aji.12227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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