Article
Polymorphism of the interleukin-1beta gene and endometriosis.
Journal of the Society for Gynecologic Investigation - 1 Apr 2003
Wieser Fritz, Hefler Lukas, Tempfer Clemens, Vlach Ulli, Schneeberger Christian, Huber Johannes, Wenzl Rene
Abstract excerpt
OBJECTIVE: Experimental data indicate that interleukin (IL)-1 plays a role in the pathogenesis of endometriosis. We determined the genotype and the allele frequencies of the IL1B exon 5 polymorphism and the corresponding IL-1beta serum levels in women with endometriosis. METHODS: We genotyped 92 women with surgically and histologically confirmed endometriosis and 69 controls without history of endometriosis. Both...
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