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Article

Effects of dietary transition metals on oxidative DNA lesions in neonatal rats.

Mutation research - 8 Aug 2001

Zhou G D, Randerath E, Randerath K

Abstract excerpt

Bulky endogenous oxidative lesions (type II I-compounds) reflect DNA damage associated with oxidative stress. As shown by 32P-postlabeling, their levels are enhanced by pro-oxidant genotoxins and also shortly after normal birth in several rat tissues as a function of time and the maternal diet. In order to elucidate which dietary components contribute to postnatal DNA damage, we have focused, herein, on the...

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PMID: 11470482
DOI: 10.1016/s0027-5107(01)00148-8

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