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Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.

Disease models & mechanisms - 1 Oct 2016

Tarry-Adkins Jane L, Fernandez-Twinn Denise S, Chen Jian Hua, Hargreaves Iain P, Neergheen Viruna, Aiken Catherine E, Ozanne Susan E

Abstract excerpt

'Developmental programming', which occurs as a consequence of suboptimal in utero and early environments, can be associated with metabolic dysfunction in later life, including an increased incidence of cardiovascular disease and type 2 diabetes, and predisposition of older men to sarcopenia. However, the molecular mechanisms underpinning these associations are poorly understood. Many conditions associated with...

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Identifiers

PMID: 27585884
DOI: 10.1242/dmm.026591
PMCID: PMC5087829

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OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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