Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between cadmium and aromatic DNA adducts in hprt mutagenesis during foetal development.

Mutagenesis - 1 May 2005

Godschalk Roger, Hogervorst Janneke, Albering Harma, Mercelina-Roumans Patricia, van Schooten Frederik-Jan, de Haan Jelte, Kleinjans Jos

Abstract excerpt

The foetus is exposed to multiple xenobiotics through the mother's circulation and this is possibly involved in the development of diseases in later life. Heavy metals and lipophilic genotoxins in umbilical cord blood of newborns may have synergistic effects on mutagenesis in the hypoxanthine-phosphoribosyltransferase (HPRT) reporter gene. Concentrations of zinc (Zn), lead (Pb) and cadmium (Cd) were determined in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadmium
Share to DNA Adducts

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fetal Blood

Share to Fetal Development

Share to Hypoxanthine Phosphoribosyltransferase

Share to Lymphocytes

Share to Maternal-Fetal Exchange

Share to Metals, Heavy

Source

Identifiers

PMID: 15817575
DOI: 10.1093/mutage/gei022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between cadmium and aromatic DNA adducts in hprt mutagenesis during foetal development.PMID 15817575Read ↗

Molecular epidemiologic research on the effects of environmental pollutants on the fetus.Semantic proximity Read ↗

Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single-nucleotide polymorphisms of fetal MTHFR and SOD2: a case-control study.Semantic proximity Read ↗

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort.Semantic proximity Read ↗

Significant interactions between maternal PAH exposure and single nucleotide polymorphisms in candidate genes on B[ a ]P-DNA adducts in a cohort of non-smoking Polish mothers and newborns.Semantic proximity Read ↗

The Epigenetic Effects of Prenatal Cadmium ExposureSemantic proximity Read ↗

Gene-environment interactions in heavy metal and pesticide carcinogenesis.Semantic proximity Read ↗

Benzo(a)pyrene and Cerium Dioxide Nanoparticles in Co-Exposure Impair Human Trophoblast Cell Stress SignalingSemantic proximity Read ↗

Transplacental transfer of environmental genotoxins: polycyclic aromatic hydrocarbon-albumin in non-smoking women, and the effect of maternal GSTM1 genotype.Semantic proximity Read ↗

Impact of DNA repair polymorphisms on DNA instability biomarkers induced by lead (Pb) in workers exposed to the metal.Semantic proximity Read ↗

Qualitatively and quantitatively similar effects of active and passive maternal tobacco smoke exposure on in utero mutagenesis at the HPRT locus.Semantic proximity Read ↗

Cigarette smoke‐induced transgenerational alterations in genome stability in cord blood of human F1 offspringSemantic proximity Read ↗

Exploiting gene-environment interaction to detect adverse health effects of environmental chemicals on the next generation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.