Article
Large-scale production of mouse phenotypes: the search for animal models for inherited diseases in humans.
Briefings in bioinformatics - 1 May 2001
Hrabé de Angelis M, Strivens M
Abstract excerpt
This paper is aimed principally at bioinformaticians and biologists as an introduction to recent advances in mouse mutagenesis, concentrating on genome-wide screens utilising the powerful mutagen N-ethyl-N-nitroso-urea (ENU). It contains a brief background to the underlying genetics as well as details of the practical aspects of organisation and data capture for such projects.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
