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Article

Functional characterization of Fas ligand on tumor cells escaping active specific immunotherapy.

Cell death and differentiation - 1 Jul 2001

Céfai D, Schwaninger R, Balli M, Brunner T, Gimmi C D

Abstract excerpt

Mice transgenic for the rat HER-2/neu oncogene (rNeu-TG) developed spontaneous breast tumors that can escape a rNeu-specific immune response induced by active specific immunotherapy (ASI). The ability of these escape tumors to grow appeared to be due to upregulation of the Fas ligand (Fas-L) molecule. In an effort to develop tools for the better elucidation of the role of Fas-L and other regulatory mechanisms in...

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PMID: 11464213
DOI: 10.1038/sj.cdd.4400862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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