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Article

Activation of Akt as a mechanism for tumor immune evasion.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Mar 2009

Noh Kyung Hee, Kang Tae Heung, Kim Jin Hee, Pai Sara I, Lin Ken Y, Hung Chien-Fu, Wu T-C, Kim Tae Woo

Abstract excerpt

Immune evasion is an important reason why the immune system cannot control tumor growth. To elucidate the mechanism for tumor immune evasion, we generated an immune-resistant human papillomavirus type 16 (HPV-16) E7-expressing tumor cell line by subjecting a susceptible tumor cell line to multiple rounds of in vivo immune selection with an E7-specific vaccine. Comparison of parental and immune-resistant tumors...

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Identifiers

PMID: 19107122
DOI: 10.1038/mt.2008.255
PMCID: PMC2835083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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