Article
Imprinting in the germ line.
Stem cells (Dayton, Ohio) - 1 Jan 2001
Mann J R
Abstract excerpt
Genomic imprinting is an epigenetic system of gene regulation in mammals. It determines the parent-of-origin-dependent expression of a small number of imprinted genes during development, i.e., the maternal allele is inactive while the paternal is active, or vice versa. Imprinting is imparted in the germ line and involves differential DNA methylation such that particular DNA regions become methylated in one sex of...
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