Article
Mechanisms of imprint dysregulation.
American journal of medical genetics. Part C, Seminars in medical genetics - 15 Aug 2010
Horsthemke Bernhard
Abstract excerpt
Genomic imprinting is an epigenetic process by which the male and the female germ line confer specific marks (imprints) onto certain gene regions, so that one allele of an imprinted gene is active and the other allele is silent. Genomic imprints are erased in primordial germ cells, newly established during later stages of germ cell development, and stably inherited through somatic cell divisions during...
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