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Genomic imprinting and reproduction

23 Sept 2005

Abstract excerpt

Genomic imprinting is the parent-of-origin specific gene expression which is a vital mechanism through both development and adult life. One of the key elements of the imprinting mechanism is DNA methylation, controlled by DNA methyltransferase enzymes. Germ cells undergo reprogramming to ensure that sex-specific genomic imprinting is initiated, thus allowing normal embryo development to progress after...

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PMID: 16183857
DOI: 10.1530/rep.1.00395

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