Article
The relationship between translational control and mRNA degradation for the Escherichia coli threonyl-tRNA synthetase gene.
Journal of molecular biology - 20 Jul 2001
Nogueira T, de Smit M, Graffe M, Springer M
Abstract excerpt
Expression of thrS, the gene encoding Escherichia coli threonyl-tRNA synthetase, is negatively autoregulated at the translational level. Regulation is due to the binding of threonyl-tRNA synthetase to its own mRNA at a site called the operator, located immediately upstream of the initiation codon. The present work investigates the relationship between regulation and mRNA degradation. We show that two regulatory...
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