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Article

Association of polymorphisms of the serotonergic system with smoking initiation in Caucasians.

Drug and alcohol dependence - 1 Apr 2010

Iordanidou Maria, Tavridou Anna, Petridis Ioannis, Kyroglou Soultana, Kaklamanis Loukas, Christakidis Dimitrios, Manolopoulos Vangelis G

Abstract excerpt

BACKGROUND: The serotonergic system may be implicated in susceptibility to nicotine dependence as nicotine increases 5-hydroxytryptamine (5-HT) release in brain and symptoms of nicotine withdrawal may be modulated by diminished serotonergic neurotransmission. We examined the association of polymorphisms of genes involved in release and receptor function of 5-HT with cigarette smoking initiation in subjects of...

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Identifiers

PMID: 20060656
DOI: 10.1016/j.drugalcdep.2009.11.015

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