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Article

Intracellular association of a mutant insulin-like growth factor receptor with endogenous receptors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2001

Reiss K, Tu X, Romano G, Peruzzi F, Wang J Y, Baserga R

Abstract excerpt

The type 1 insulin-like growth factor receptor (IGF-IR) is emerging as a powerful survival factor against a variety of apoptotic agents in many cell types. A mutant IGF-IR designated 486/STOP is known to induce apoptosis and inhibit the growth of human tumor cells in mice. We have investigated th...

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PMID: 11448933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11448933-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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