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Article

Assembly and enzymatic properties of the catalytic domain of human complement protease C1r.

The Journal of biological chemistry - 28 Sept 2001

Lacroix M, Ebel C, Kardos J, Dobó J, Gál P, Závodszky P, Arlaud G J, Thielens N M

Abstract excerpt

The catalytic properties of C1r, the protease that mediates activation of the C1 complex of complement, are mediated by its C-terminal region, comprising two complement control protein (CCP) modules followed by a serine protease (SP) domain. Baculovirus-mediated expression was used to produce fragments containing the SP domain and either 2 CCP modules (CCP1/2-SP) or only the second CCP module (CCP2-SP). In each...

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Identifiers

PMID: 11445589
DOI: 10.1074/jbc.M105688200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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