Article
Evidence that longer androgen receptor polyglutamine repeats are a causal factor for genital abnormalities.
The Journal of clinical endocrinology and metabolism - 1 Jul 2001
Lim H N, Nixon R M, Chen H, Hughes I A, Hawkins J R
Abstract excerpt
Moderate to severe undermasculinized genitalia was recently shown to be associated with longer polyglutamine repeats within the androgen receptor [AR(Gln)n]. However, it was unknown whether this was because longer AR(Gln)n contributed to the: 1) etiology; 2) severity; and/or 3) testicular maldescent. Therefore, AR(Gln)n length in 175 males with abnormal genitalia were analyzed according to etiology (known or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.