Androgen receptor gene CAG and GGC repeat lengths in cryptorchidism

Abstract excerpt

OBJECTIVE: Cryptorchidism is the most common congenital birth defect in male children, and accumulating evidence suggests that genetic abnormalities may be associated with it. The androgen receptor has two polymorphic sites in exon 1, with different numbers of CAG and GGC repeats, resulting in variable lengths of polyglutamine and polyglycine stretches. Longer CAG repeats result in a reduced androgen receptor...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hormonal and reproductive studies
• Share to Ovarian function and disorders
• Share to Sexual Differentiation and Disorders