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Article

Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys.

The Journal of clinical endocrinology and metabolism - 1 Mar 2012

Davis-Dao Carol, Koh Chester J, Hardy Brian E, Chang Andy, Kim Steve S, De Filippo Roger, Hwang Andrew, Pike Malcolm C, Carroll Joshua D, Coetzee Gerhard A, Vandenberg David, Siegmund Kimberly, Cortessis Victoria K

Abstract excerpt

CONTEXT: Cryptorchidism is the most frequent congenital malformation among males, the major established risk factor for testicular germ cell tumors, and a presumed infertility risk factor. Androgens are essential for testicular descent, and functional genetic polymorphisms in the androgen receptor gene (AR) are postulated to influence cryptorchidism risk. OBJECTIVE: The aim of the study was to investigate whether...

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PMID: 22188741
DOI: 10.1210/jc.2011-2439

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