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Article

Effect of apolipoprotein E genotype on cerebral autoregulation during cardiopulmonary bypass.

Stroke - 1 Jul 2001

Ti L K, Mathew J P, Mackensen G B, Grocott H P, White W D, Reves J G, Newman M F

Abstract excerpt

BACKGROUND AND PURPOSE: The presence of the apolipoprotein E epsilon4 (apoE4) allele has been associated with cognitive decline after cardiac surgery. We compared autoregulation of cerebral blood flow (CBF), cerebral metabolic rate for oxygen (CMRO(2)), and arterial-venous oxygen content difference [C(A-V)O(2)], during cardiopulmonary bypass (CPB) in patients with and without the apoE4 allele to help define the...

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Source

Identifiers

PMID: 11441194
DOI: 10.1161/01.str.32.7.1514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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