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Article

The apolipoprotein E epsilon4 allele is not associated with cognitive dysfunction in cardiac surgery.

The Annals of thoracic surgery - 1 Sept 2008

Silbert Brendan S, Evered Lisbeth A, Scott David A, Cowie Tiffany F

Abstract excerpt

BACKGROUND: The plasma protein apolipoprotein E (APOE) is a risk factor for degenerative cognitive decline manifested by mild cognitive impairment and later by Alzheimer's disease. Patients undergoing coronary artery bypass grafting (CABG) are known to have a high prevalence of preexisting cognitive impairment and postoperative cognitive dysfunction. Because both mild cognitive impairment and Alzheimer's disease...

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Source

Identifiers

PMID: 18721571
DOI: 10.1016/j.athoracsur.2008.04.085

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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