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Article

Segregation of nuclear and membrane-initiated actions of estrogen receptor using genetically modified animals and pharmacological tools.

Molecular and cellular endocrinology - 1 Jan 2022

Adlanmerini Marine, Fontaine Coralie, Gourdy Pierre, Arnal Jean-François, Lenfant Françoise

Abstract excerpt

Estrogen receptor alpha (ERα) and beta (ERβ) are members of the nuclear receptor superfamily, playing widespread functions in reproductive and non-reproductive tissues. Beside the canonical function of ERs as nuclear receptors, in this review, we summarize our current understanding of extra-nuclear, membrane-initiated functions of ERs with a specific focus on ERα. Over the last decade, in vivo evidence has...

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Identifiers

PMID: 34626731
DOI: 10.1016/j.mce.2021.111467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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