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Article

E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase epsilon B-subunit gene POLE2.

Nucleic acids research - 1 Jul 2001

Huang D, Jokela M, Tuusa J, Skog S, Poikonen K, Syväoja J E

Abstract excerpt

The B-subunits of replicative DNA polymerases from Archaea to humans belong to the same protein family, suggesting that they share a common fundamental function. We report here the gene structure for the B-subunit of human DNA polymerase epsilon (POLE2), whose expression and transcriptional regulation is typical for replication proteins with some unique features. The 75 bp core promoter region, located within...

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Source

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Identifiers

PMID: 11433027
DOI: 10.1093/nar/29.13.2810
PMCID: PMC55767

Genes

POLE2
POLA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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