Article
Analysis of the monocyte chemoattractant protein 1 -2518 promoter polymorphism in Korean patients with alopecia areata.
Journal of Korean medical science - 1 Feb 2006
Hong Seok-Beom, Jin Sheng-Yu, Park Hae-Jeong, Jung Joo-Ho, Sim Woo-Young
Abstract excerpt
Monocyte chemoattractant protein-1 (MCP-1) levels are increased in scalp lesions of patients with alopecia areata (AA), suggesting a role in the development of AA. Recently, a biallelic A/G polymorphism in the MCP-1 promoter at position -2518 has been found, influencing the level of MCP-1 expression in response to an inflammatory stimulus. We investigated whether the presence of these polymorphisms were...
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