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Article

Inhibitor IkappaBalpha promoter functional polymorphisms in patients with rheumatoid arthritis.

Journal of clinical immunology - 1 Sept 2010

Li Ruei-Nian, Hung Yu-Hung, Lin Chia-Hui, Chen Yen-Hsu, Yen Jen-Hsien

Abstract excerpt

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammation disease that may involve extra-articular organs in addition to joints. Many proinflammatory cytokines are involved in the inflammatory process of RA. IkappaBalpha conjugates with NF-kappaB and is a key player in regulation of the inflammatory process. We carried out experiments to define the effect of different promoter polymorphisms on the...

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Identifiers

PMID: 20563630
DOI: 10.1007/s10875-010-9439-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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