Article
Mutations of the 3' untranslated region of the SDF1 gene in apes and monkeys: potential impact on sensitivity to AIDS induced by lentiviruses.
AIDS (London, England) - 6 Jul 2001
Puissant B, Blancher A
Abstract excerpt
The comparison of the stromal cell-derived factor-1 (SDF1) gene 3' untranslated region (3'UTR) of four great ape and four monkey species with their human counterparts shows that the human SDF1-3'A mutation is present in primate species that are the most susceptible to lentivirus-induced AIDS and is absent in species that are particularly resistant to lentivirus-induced AIDS. The results enlighten the possible...
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