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Article

The role of a stromal cell-derived factor-1 chemokine gene variant in the clinical course of HIV-1 infection.

AIDS (London, England) - 18 Jun 1998

van Rij R P, Broersen S, Goudsmit J, Coutinho R A, Schuitemaker H

Abstract excerpt

BACKGROUND: A G-to-A transition in the 3' untranslated region (UTR) of stromal cell-derived factor (SDF)-1 gene (SDF1-3'A) has recently been described, which in the homozygous state was associated with delayed disease progression. OBJECTIVE: To analyse the effect of the SDF-1 polymorphism on AIDS-free survival and survival after AIDS diagnosis, also in relation to viral phenotype. DESIGN: Retrospective...

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PMID: 9662191

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