Article
The role of a stromal cell-derived factor-1 chemokine gene variant in the clinical course of HIV-1 infection.
AIDS (London, England) - 18 Jun 1998
van Rij R P, Broersen S, Goudsmit J, Coutinho R A, Schuitemaker H
Abstract excerpt
BACKGROUND: A G-to-A transition in the 3' untranslated region (UTR) of stromal cell-derived factor (SDF)-1 gene (SDF1-3'A) has recently been described, which in the homozygous state was associated with delayed disease progression. OBJECTIVE: To analyse the effect of the SDF-1 polymorphism on AIDS...
Topics
- Acquired Immunodeficiency Syndrome
- Chemokine CXCL12
- Chemokines, CXC
- Disease Progression
- Follow-Up Studies
- Genetic Variation
- Genotype
- HIV-1
- Homosexuality, Male
- Humans
- Longitudinal Studies
- Male