Article
Cerebrospinal fluid response to structured treatment interruption after virological failure.
AIDS (London, England) - 6 Jul 2001
Price R W, Paxinos E E, Grant R M, Drews B, Nilsson A, Hoh R, Hellmann N S, Petropoulos C J, Deeks S G
Abstract excerpt
OBJECTIVE: Structured antiretroviral treatment interruption (STI) has been advocated as a therapeutic strategy for HIV-1 infection. We report initial observations of cerebrospinal fluid (CSF) HIV-1 infection in five patients undergoing serial lumbar punctures (LPs) during STI undertaken following virological failure. DESIGN AND METHODS: In this prospective observational study we quantified HIV-1 RNA...
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