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Article

Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21.

Journal of bacteriology - 1 Jul 2001

Gregory S T, Cate J H, Dahlberg A E

Abstract excerpt

Spontaneous, erythromycin-resistant mutants of Thermus thermophilus IB-21 were isolated and found to carry the mutation A2058G in one of two 23S rRNA operons. The heterozygosity of these mutants indicates that A2058G confers a dominant or codominant phenotype in this organism. This mutation provides a valuable tool for the genetic manipulation of the 23S rRNA genes of Thermus.

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Share to Drug Resistance, Microbial
Share to Drug Resistance, Multiple
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Bacterial

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Share to RNA, Ribosomal, 23S

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Source

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Identifiers

PMID: 11418580
DOI: 10.1128/JB.183.14.4382-4385.2001
PMCID: PMC95329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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