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Article

ICP34.5 influences herpes simplex virus type 1 maturation and egress from infected cells in vitro.

The Journal of general virology - 1 Dec 1994

Brown S M, MacLean A R, Aitken J D, Harland J

Abstract excerpt

We have previously demonstrated that efficient replication of mutant herpes simplex virus which fails to synthesize the polypeptide ICP34.5 is cell type and cell state dependent. ICP34.5 negative viruses do not grow in stationary state mouse embryo fibroblast 3T6 cells whereas the growth kinetics in BHK cells are indistinguishable from those of wild-type. We now demonstrate that this defect is not due to an...

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PMID: 7996163
DOI: 10.1099/0022-1317-75-12-3679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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ICP34.5 influences herpes simplex virus type 1 maturation and egress from infected cells in vitro.PMID 7996163Read ↗

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