ICP34.5 influences herpes simplex virus type 1 maturation and egress from infected cells in vitro.

doi:10.1099/0022-1317-75-12-3679

Back to search

Article

ICP34.5 influences herpes simplex virus type 1 maturation and egress from infected cells in vitro.

The Journal of general virology - 1 Dec 1994

Brown S M, MacLean A R, Aitken J D, Harland J

Abstract excerpt

We have previously demonstrated that efficient replication of mutant herpes simplex virus which fails to synthesize the polypeptide ICP34.5 is cell type and cell state dependent. ICP34.5 negative viruses do not grow in stationary state mouse embryo fibroblast 3T6 cells whereas the growth kinetics...

Topics

Animals
Cell Division
Cell Line
Cricetinae
Cytopathogenic Effect, Viral
Extracellular Space
Fibroblasts
Herpesvirus 1, Human
Mice
Mutation
Nuclear Envelope
Viral Proteins
Virion
Virus Replication

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.