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Article

Genetic mechanisms for hypersensitivity and resistance to the anticoagulant Warfarin.

Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2001

Linder M W

Abstract excerpt

Warfarin is the therapeutic of choice for maintenance anticoagualtion therapy. A principle caveat of this medication is that the dosage required to achieve the desired therapeutic effect varies up to 120-fold between individuals. Currently, there are no reliable means of prospectively identifying which patients will require either unusually high or low dosages. This dilemma puts patients at risk of therapeutic...

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Identifiers

PMID: 11412812
DOI: 10.1016/s0009-8981(01)00420-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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