Article
Genetic polymorphisms and atrial fibrillation: Insights into the prothrombotic state and thromboembolic risk.
Annals of medicine - 1 Dec 2010
López-Cuenca Angel, Marín Francisco, Roldán Vanessa, González-Conejero Rocío, Hernández-Romero Diana, Valdés Mariano, Lip Gregory Y H
Abstract excerpt
The pathophysiology of thromboembolism in atrial fibrillation (AF) is a multifactorial and complex process. Abnormalities of haemostasis, fibrinolysis, endothelium, and platelets have all been described in AF. This prothrombotic state observed in AF appears to be additive to the presence of clinical and echocardiography risk factors for thromboembolism. Nonetheless, the precise mechanistic pathway(s) leading to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
