Hematology consult: high-sensitivity warfarin genotype.

Abstract excerpt

Warfarin sensitivity genotyping should be considered in patients who require multiple dosing adjustments to maintain a therapeutic international normalized ratio (INR)--patients with a history of bleeding/thrombosis when taking warfarin or patients who are being started on warfarin therapy for the first time. Studies showed that individuals with genetic variants require a longer time to achieve stable dosing,...

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