Article
The TaqI A DRD2 polymorphism in type II alcohol dependence: a marker of age at onset or of a familial disease?
Alcohol (Fayetteville, N.Y.) - 1 Jun 2009
Pinto Emmanuel, Reggers Jean, Gorwood Philip, Boni Claudette, Scantamburlo Gabrielle, Pitchot William, Ansseau Marc
Abstract excerpt
Cloninger's type II is a severe, early-onset, male-limited, and genetically influenced, impulsive form of alcoholism. Significant association has been reported between the A1 allele of the D2 dopamine receptor (DRD2) gene, substance misuse and personality traits of impulsivity and novelty seeking. We assessed the association between the TaqI A DRD2 gene polymorphism with Cloninger's typology and family history of...
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