Article
Do alcohol-dependent individuals with DRD2 A1 allele have an increased risk of relapse? A pilot study.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Dahlgren Angelica, Wargelius Hanna-Linn, Berglund Kristina J, Fahlke Claudia, Blennow Kaj, Zetterberg Henrik, Oreland Lars, Berggren Ulf, Balldin Jan
Abstract excerpt
AIMS: The TaqIA polymorphism of the dopamine D2 receptor (DRD2) gene has been extensively studied in relation to alcoholism, and the TaqI A1 allele appears to be over-represented in alcohol-dependent individuals. In a recent study, this allele has also been associated with a highly increased mortality rate in alcohol-dependent individuals. In the present study, we investigated whether the TaqI A1 allele of the...
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