Article
Expression of int-2 oncogene in Kaposi's sarcoma lesions.
The Journal of clinical investigation - 1 Mar 1993
Huang Y Q, Li J J, Moscatelli D, Basilico C, Nicolaides A, Zhang W G, Poiesz B J, Friedman-Kien A E
Abstract excerpt
Fibroblast growth factors (FGFs), such as basic FGF, have been implicated in the growth of Kaposi's sarcoma (KS) cells in vitro. In the evaluation of the expression of the various genes of the different members of the FGF family and their receptors in fresh KS tissue specimens, int-2 was found to be expressed in more than half of the KS tumors examined. Using reverse transcription PCR, the expression of int-2 was...
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