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Article

Insulin-like growth factor -I deficiency.

Hormone research - 1 Jan 2001

Camacho-Hübner C, Savage M

Abstract excerpt

The insulin-like growth factor (IGF) system composed of two ligands, their receptors and regulatory proteins (acid-labile subunit and IGF-binding proteins) plays a central role in the regulation of growth and development in mammals. In addition to its key role in the stimulation of cellular proliferation and growth, IGF-I has important effects on carbohydrate, protein and bone metabolism. The molecular biology...

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PMID: 11408756
DOI: 10.1159/000063457

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