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Article

IGF-I in human growth: lessons from defects in the GH-IGF-I axis.

Nestle Nutrition Institute workshop series - 1 Jan 2013

Hwa Vivian, Fang Peng, Derr Michael A, Fiegerlova Eva, Rosenfeld Ron G

Abstract excerpt

The IGF system plays a critical role in all phases of human growth, including intrauterine, childhood and pubertal. The importance of IGF-I for both in utero as well as postnatal human growth is highlighted by rare human homozygous IGF1 mutations, which are characterized by intrauterine growth retardation (IUGR), microcephaly, mental retardation and severe postnatal growth failure. Clinical conditions of IGF-I...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23502138
DOI: 10.1159/000342548

Genes

IGFALS
GHR
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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