Article
Advances in the Genetics and Biology of Pancreatic Cancer.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Aguirre Andrew J, Collisson Eric A
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDA) remains one of the most devastating diagnoses in modern medicine. While the clinical management of the disease has improved, the complex biologic underpinnings of PDA enable both its aggressive nature and slow clinical translational progress. In this review, we provide an overview of the key features of PDA genetics and biology, highlighting translational challenges and...
Topics
- Animals
- Cell Transformation, Neoplastic
- Energy Metabolism
- Gene Expression Regulation, Neoplastic
- Genes, ras
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genomics
- Humans
- Pancreatic Neoplasms
- Translational Research, Biomedical