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Article

Relationship between perioperative oncological evaluation and recurrence using circulating tumor DNA with KRAS mutation in patients with colorectal cancer.

Cancer medicine - 1 Aug 2022

Hayashi Takaomi, Yoshida Yoichiro, Yamada Teppei, Tanaka Keita, Shimaoka Hideki, Kajitani Ryuji, Munechika Taro, Nagano Hideki, Matsumoto Yoshiko, Komono Akira, Sakamoto Ryohei, Aisu Naoya, Yoshimatsu Gumpei, Yoshimura Fumihiro, Hasegawa Suguru

Abstract excerpt

BACKGROUND: The detection of circulating tumor DNA (ctDNA) in colorectal cancer (CRC) by liquid biopsy may have prognostic information. In this perioperative study, we evaluate if there is a relationship between mutant allele frequency (MAF) of Kirsten rat sarcoma viral oncogene homolog (KRAS) and tumor recurrence and how that could be useful in the early detection of recurrence. METHODS: Among 304 cases of...

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Identifiers

PMID: 35312176
DOI: 10.1002/cam4.4677
PMCID: PMC9385586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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