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Article

Transgenic mouse models of tauopathies: prospects for animal models of Pick's disease.

Neurology - 1 Jun 2001

Lee V M, Trojanowski J Q

Abstract excerpt

Because filamentous neuronal tau inclusions are neuropathologic hallmarks of Pick's disease and a number of other neurodegenerative disorders known as tauopathies, the authors generated lines of transgenic (Tg) mice that overexpress the shortest human tau isoform in the CNS. These Tg mice accumulated argyrophilic and filamentous tau immunoreactive neuronal inclusions with age in cortex and brainstem as well as in...

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Source

Identifiers

PMID: 11402147
DOI: 10.1212/wnl.56.suppl_4.s26

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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