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Invited review: Animal models of tauopathies and their implications for research/translation into the clinic

26 Nov 2014

Abstract excerpt

Our aims are to review animal models of tauopathies, which include a number of brain disorders with various aetiologies, including ageing, genetics, infectious diseases, toxins, trauma and other unknown factors. Tauopathies are characterized by the accumulation of filaments of the microtubule-associated tau protein. The different aetiopathogeneses and distinct molecular events involved in tau aggregation have led...

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PMID: 25428793
DOI: 10.1111/nan.12200

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