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Article

Genetic Neurodegenerative Diseases: The Human Illness and Transgenic Models

6 Nov 1998

Abstract excerpt

Review The neurodegenerative disorders, a heterogeneous group of chronic progressive diseases, are among the most puzzling and devastating illnesses in medicine. Some of these disorders, such as Alzheimer's disease, amyotrophic lateral sclerosis, the prion diseases, and Parkinson's disease, can occur sporadically and, in some instances, are caused by inheritance of gene mutations. Huntington's disease is acquired...

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PMID: 9804539
DOI: 10.1126/science.282.5391.1079

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