Article
Septic shock and respiratory failure in community-acquired pneumonia have different TNF polymorphism associations.
American journal of respiratory and critical care medicine - 1 Jun 2001
Waterer G W, Quasney M W, Cantor R M, Wunderink R G
Abstract excerpt
Genetic factors are likely to contribute to the variable presentation of community-acquired pneumonia (CAP). The purpose of this prospective cohort study was to determine whether the LTalpha+250 (TNFbeta+250) and TNFalpha-308 gene polymorphisms are associated with different presentations of CAP. Septic shock (SS) was defined using American College of Chest Physicians/Society of Critical Care Medicine (ACCP-SCCM)...
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