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Article

Complex relationship between acquisition of beta-lactam resistance and loss of virulence in Streptococcus pneumoniae.

The Journal of infectious diseases - 1 Jul 2001

Rieux V, Carbon C, Azoulay-Dupuis E

Abstract excerpt

In a previous study of a murine peritonitis model, no Streptococcus pneumoniae strains were found that were both clinically penicillin resistant and virulent. This study assessed the relationship between acquired resistance and virulence in single- and double-isogenic penicillin-resistant (Peni-R) mutants obtained by transformation of a virulent penicillin-susceptible recipient strain with pbp2b and pbpX...

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Source

Identifiers

PMID: 11398111
DOI: 10.1086/320992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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