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Article

Activation of cAMP-dependent protein kinase increases the protein level of steroidogenic factor-1.

Endocrinology - 1 Jan 2002

Aesøy Reidun, Mellgren Gunnar, Morohashi Ken-Ichirou, Lund Johan

Abstract excerpt

The orphan nuclear receptor steroidogenic factor 1 (SF-1) is an essential regulator of endocrine organogenesis, sexual differentiation, and steroidogenesis. SF-1 is a transcriptional regulator of cAMP responsive genes, but the exact mechanisms by which cAMP-dependent PKA modulates SF-1 dependent transcription leading to increased steroidogenic output have not been determined. In this report the effects of PKA...

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PMID: 11751621
DOI: 10.1210/endo.143.1.8599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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