Article
A common mutation in the gene for coagulation factor XIII-A (VAL34Leu): a risk factor for primary intracerebral hemorrhage is protective against atherothrombotic diseases.
American journal of hematology - 1 Jul 2001
Gemmati D, Serino M L, Ongaro A, Tognazzo S, Moratelli S, Resca R, Moretti M, Scapoli G L
Abstract excerpt
The role of a common polymorphism in the factor XIII A-subunit gene (FXIII Val34Leu) has been recently investigated as a protective genetic factor against arterial and venous thrombosis. In addition, the less frequent Leu34 allele has been described as a risk factor for intracerebral hemorrhage. We evaluated the prevalence of this polymorphism by PCR in three case-control studies of patients diagnosed as having...
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