Article
Genetic polymorphism of LDLR (rs688) is associated with primary intracerebral hemorrhage.
Current neurovascular research - 1 Feb 2014
Lee Jiann-Der, Hsiao Kuang-Ming, Lee Tsong-Hai, Kuo Ya-Wen, Huang Yen-Chu, Hsu Huan-Lin, Lin Ya-Hui, Wu Chih-Ying, Huang Ying-Chih, Lee Meng, Yang Hsin-Ta, Hsu Chia-Yu, Pan Yi-Ting
Abstract excerpt
Intracranial hemorrhage is the third most common cause of cerebrovascular disease. Some polymorphisms that affect clotting factors increase the risk of thrombosis. However, few reports have analyzed the effect of polymorphisms on the hemostatic state in bleeding disorders. The low-density lipoprotein receptor (LDLR) has been shown to contribute to factor VIII (FVIII) homeostasis, which represents a link between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.