Article
Factor XIII Val 34 Leu: a novel association with primary intracerebral hemorrhage.
Stroke - 1 Apr 1998
Catto A J, Kohler H P, Bannan S, Stickland M, Carter A, Grant P J
Abstract excerpt
BACKGROUND AND PURPOSE: A common G-to-T point mutation (Val 34 Leu) in exon 2 of the alpha-subunit of the factor XIII is strongly negatively associated with the development of myocardial infarction. This result suggests that factor XIII Val 34 Leu is interfering with the formation of cross-linked fibrin. The role of factor XIII Val 34 Leu in the pathogenesis of cerebral infarction and primary intracerebral...
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