Article
Fc receptor-mediated phagocytosis makes a significant contribution to clearance of influenza virus infections.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2001
Huber V C, Lynch J M, Bucher D J, Le J, Metzger D W
Abstract excerpt
Fc receptors for IgG expressed on macrophages and NK cells are important mediators of opsonophagocytosis and Ab-dependent cell-mediated cytotoxicity. Phagocyte-mediated opsonophagocytosis is pivotal for protection against bacteria, but its importance in recovery from infection with intracellular pathogens is unclear. We have now investigated the role of opsonophagocytosis in protection against lethal influenza...
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